Eliot C. Bush

Professor of Biology

F.W. Olin Science Center, Room 1240
301 Platt Blvd.
Claremont, CA 91711

Schedule/calendar (viewable with g.hmc.edu account)

Education and professional experience

  • AB, Harvard University
  • PhD, California Institute of Technology
  • Postdoctoral Fellow, University of Chicago

Research interests

Our current work is in the area of microbial genome evolution. We’ve developed a computational approach to reconstructing the history of genomic island insertions in clades of closely related microbes (link to xenoGI site). We are now improving various aspects of this method, and using it to study patterns of horizontal transfer across the tree of life. Additional information can be found at our lab web site.

For a wider audience



Computational biology textbook

  • Libeskind-Hadas R, and Bush E. Computing for Biologists: Python Programming and Principles. Cambridge University Press. 2014.

Selected articles and chapters

  • *Liu J, Mawhorter R, *Liu I, *Santichaivekin S, Bush E, Libeskind-Hadas R. Maximum Parsimony Reconciliation in the DTLOR Model. BMC Bioinformatics. 22(394). 2021. [article]
  • Bush EC, Adolph SC, Donaldson-Matasci MC, Hur JH, and Schulz D. Incorporating Programming, Modeling and Data Analysis into an Introductory Biology Course. Journal of College Science Teaching. 50(3). 2021. [article] [pdf]
  • Bush EC, *Clark AE, *DeRanek CA, *Eng A, *Forman J, *Heath K, *Lee AB, Stoebel DM, *Wang Z, *Wilber M, *Wu H. xenoGI: reconstructing the history of genomic island insertions in clades of closely related bacteria. BMC Bioinformatics. 19(32). 2018. [article] [bioRxiv preprint]
  • *Wong GT, Bonocora RP, *Schep AN, *Beeler SM, Fong AJ, *Shull LM, Batachari LE, *Dillon M, Evans C, *Becker CJ, Bush EC, Hardin J, Wade JT, and Stoebel DM. Genome-Wide Transcriptional Response to Varying RpoS Levels in Escherichia coli K-12. J Bacteriol. 199:e00755-16. 2017.
  • Drewell, RA, Bush EC, Remnant EJ, *Wong GT, *Beeler SM, *Stringham JL, Lim J, Gouldie F, and Oldroyd BP. The dynamic DNA methylation cycle from egg to sperm in the honey bee Apis mellifera. Development. 141(13):2702-11. 2014.
  • *Beeler, SM, *Wong GT, Zheng JM, Bush EC, Remnant EJ, Oldroyd BP, and Drewell RA. Whole Genome DNA Methylation Profile of the Jewel Wasp (Nasonia vitripennis). G3: Genes Genomes Genetics, g3-113. 2013.
  • Bush EC, Clark AE*, DeBoever CM*, Haynes LE*, Hussain S*, Ma S*, McDermott MM*, Novak AM*, Wentworth JS*. (2012) Modeling the Role of Negative Cooperativity in Metabolic Regulation and Homeostasis. PLoS ONE 7(11): e48920. [article]
  • Nevarez PA*, DeBoever CM*, Freeland B*J, Quitt MA* & Bush EC. Context dependent substitution biases vary within the human genome. BMC Bioinformatics11(462). 2010. [article]

* undergraduate author

Complete publication list