Querying Latent Structure in Single-cell RNA-seq Data

Memorial Sloan Kettering Cancer Center Computer Science, 2022–23

Liaison(s): Dr. Roshan Sharma
Advisor(s): Dr. Naim Matasci, Jim Boerkoel
Students(s): Sonia Bliss, Austin Froelich, Kate Phillips (PM-F), Brian Simpkins (PM-S)

Memorial Sloan Kettering Cancer Center (MSKCC) is a private cancer research and treatment facility located in New York City. Within MSKCC, the Dana Pe’er lab has developed a novel single-cell analysis tool called SPECTRA for identifying meaningful biological factors in a single-cell RNA-seq data. This project, in collaboration with the SAIL (Single-Cell Analytics Innovation Lab) at MSKCC (directed by Dana Pe’er), intends to create a graphical user interface (GUI) for SPECTRA, modify the source code to support GPU computation, and explore potential integration with other single-cell analytics tools.