Optimization of a Recombinant Protein Product Through the Analysis of Filtration in the Projection Process
January 1, 2007Amgen Inc. Global, 2006-07
Liaison(s): Thomas Kelleher, Anthony Tran
Advisor(s): Anthony Bright, Elsie Pares-Matos (UPRM-University of Puerto Rico Mayaguez), Lorenzo Saliceti (UPRM)
Students(s): Felicia Nan, Kenneth Estevez (UPRM), Elisa Alfaro (UPRM), Solimar Diaz UPRM), Mackenzie Miller, Heather Schalliol
Amgen wanted the Amgen Global Clinic Team to explore sialidase inhibition and membrane filtration to optimize conditions for improving the amount of usable recombinant protein product. The HMC engineering students and the UPRM biotechnology students have been collaborating to understand sialidase activity as well as characterize different types of membranes within the filtration process.