{"id":13561,"date":"2024-10-16T08:55:07","date_gmt":"2024-10-16T15:55:07","guid":{"rendered":"https:\/\/www.hmc.edu\/about\/?p=13561"},"modified":"2024-12-06T17:03:22","modified_gmt":"2024-12-07T01:03:22","slug":"study-published-by-vosburg-and-students-shows-surprising-result","status":"publish","type":"post","link":"https:\/\/www.hmc.edu\/about\/2024\/10\/16\/study-published-by-vosburg-and-students-shows-surprising-result\/","title":{"rendered":"Carbon-carbon Bonds Study Published by Vosburg and Students Shows Surprising Result"},"content":{"rendered":"\n<p>Creating carbon-carbon bonds using mild, effective and environmentally friendly methods is a surprising result featured in a newly published paper by Donald A. Strauss Professor of Chemistry David Vosburg and four students\u2014Sydney Neibert \u201924, Kasey Chung \u201925, Grant Miller POM \u201925 and Johnson Ho \u201927. The paper, featured in the American Chemical Society journal <em>Organic Letters<\/em>, is the third for Vosburg\u2019s team published in collaboration with Greg Beutner, a process chemist at global pharmaceutical Bristol Myers Squibb (BMS).<\/p>\n\n\n\n<p>In previously published findings, Vosburg\u2019s team and BMS collaborators demonstrated safer and \u201c<a href=\"https:\/\/www.hmc.edu\/about\/2019\/12\/12\/hmc-chemistry-joins-green-chemistry-commitment\/\">greener<\/a>\u201d ways to form <a href=\"https:\/\/www.hmc.edu\/about\/2022\/10\/25\/industrial-academic-collaboration-yields-new-chemistry-teaching-lab\/\">carbon-nitrogen<\/a>, carbon-oxygen and carbon-sulfur bonds. The latest paper features their newest research finding\u2014that carbon-carbon bonds can also be created using such methods. &nbsp;<\/p>\n\n\n\n<p>\u201cOur prior results were impressive, but not necessarily surprising,\u201d says Vosburg. \u201cBeing able to make carbon-carbon bonds using this chemistry is much less expected.\u201d<br>&nbsp;<br>The team incorporated existing knowledge of relative reactivity of carbon compounds and supplemented it with computational estimates of reactivity. Vosburg credits Beutner with being an excellent collaborator and insightful co-advisor to the students. \u201cThroughout the process, this close collaboration was critical to the rapid progress and success of our work,\u201d says Vosburg.<\/p>\n\n\n\n<p>Vosburg\u2019s lab provides research students with opportunities to make medicinally useful molecules in new ways that imitate natural pathways and\/or are environmentally sustainable. Some of their target molecules can be used to fight inflammation, bacteria, fungi, tuberculosis or cancer. Often, the research team creates molecules that have never been created before.<\/p>\n\n\n\n<p>As for the students\u2019 future plans, Neibert is pursuing a PhD in chemistry at the University of Michigan. Chung, Miller and Ho\u2014who also anticipate pursuing research as PhD students after graduation\u2014will present their work at the Southern California Conference for Undergraduate Research at Cal State San Bernardino and have submitted an abstract to present at the spring 2025 national meeting of the American Chemical Society in San Diego.<\/p>\n\n\n\n<p>\u201cIt\u2019s been fabulous undertaking this research with such outstanding students,\u201d says Vosburg.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Creating carbon-carbon bonds using mild, effective and environmentally friendly methods is a surprising result featured in a newly published paper [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":13562,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6,14,967,26,30],"class_list":["post-13561","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-chemistry","category-faculty","category-general-feed","category-research","category-students"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hmc.edu\/about\/wp-json\/wp\/v2\/posts\/13561","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hmc.edu\/about\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hmc.edu\/about\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hmc.edu\/about\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hmc.edu\/about\/wp-json\/wp\/v2\/comments?post=13561"}],"version-history":[{"count":5,"href":"https:\/\/www.hmc.edu\/about\/wp-json\/wp\/v2\/posts\/13561\/revisions"}],"predecessor-version":[{"id":13696,"href":"https:\/\/www.hmc.edu\/about\/wp-json\/wp\/v2\/posts\/13561\/revisions\/13696"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hmc.edu\/about\/wp-json\/wp\/v2\/media\/13562"}],"wp:attachment":[{"href":"https:\/\/www.hmc.edu\/about\/wp-json\/wp\/v2\/media?parent=13561"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hmc.edu\/about\/wp-json\/wp\/v2\/categories?post=13561"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}