Assistant Professor of  Biology   Olin, Room 2341 301 Platt Blvd. Claremont, CA 91711 (909) 607-0653 Eliot_Bush at hmc dot edu Link to schedule/calendar   (viewable with g.hmc.edu account)

Education & professional experience

• A.B., Harvard University
• Ph.D., California Institute of Technology
• Postdoctoral Fellow, University of Chicago

Teaching

• Bio 52: Introduction to biology
• CS5 Green: a biology themed introduction to computer science
• Bio 111: Molecular biology laboratory
• Bio 118: Introduction to mathematical and computational biology
• Bio 188: Computational biology
• Bio 185: Human evolution

Research Interests

Professor Bush's research group uses computational methods to study the evolution of noncoding DNA. They are currently focusing on molecular evolutionary questions related to how nucleotide context affects the substitution process. This is part of a larger interest in understanding how changes in regulatory elements have influenced primate brain evolution. Additional information can be found at their lab web site.

Selected Publications

Bush EC, Clark AE*, DeBoever CM*, Haynes LE*, Hussain S*, Ma S*, McDermott MM*, Novak AM*, Wentworth JS*. (2012) Modeling the Role of Negative Cooperativity in Metabolic Regulation and Homeostasis. PLoS ONE 7(11): e48920. (article)

Nevarez PA*, DeBoever CM*, Freeland B*J, Quitt MA* & Bush EC. Context dependent substitution biases vary within the human genome. BMC Bioinformatics, 11(462), 2010. (article)

Bush EC & Lahn BT. A genome-wide screen for noncoding elements important in primate evolution. BMC Evolutionary Biology, 8:17, 2008. (article)

Bush EC, Allman JM. Frontal Cortex Evolution in Primates. In Larry R. Squire, Editor-in-Chief, Encyclopedia of Neuroscience, Academic Press, Oxford, 2008.

Bush EC & Lahn BT. The evolution of word composition in metazoan promoter sequence. PLoS Computational Biology, 2(11):e150, 2006. (article)

Choi SS, Bush EC, Lahn BT. Different classes of tissue-specific genes show different levels of noncoding conservation. Genomics , 87(3):433-436, 2006. (article)

Bush EC & Lahn BT. Selective Constraint on Noncoding Regions of Hominid Genomes. PLoS Computational Biology, 1(7):e73, 2005. (article)

Bush EC & Allman JM. The scaling of frontal cortex in primates and carnivores. Proceedings of the National Academy of Sciences of the United States of America, 101(11):3962-3966, 2004. (article)

Bush EC & Allman JM. The three dimensional structure and evolution of primate primary visual cortex. Anatomical Record Part A, 281A:1088-1094, 2004. (article)

Bush EC, Simons EL & Allman JM. A high resolution CT study of the cranium of a fossil anthropoid primate, Parapithecus grangeri: new insights into the evolutionary history of primate sensory systems. Anatomical Record Part A, 281A:1083-1087, 2004. (article)

Bush EC & Allman JM.The scaling of white matter to gray matter in cerebellum and neocortex. Brain Behavior and Evolution, 61(1):1-5, 2003. (article)

* undergraduate author